In bioengineering, innovation has historically emerged from serendipitous discoveries in nature's functions. However, the advent of generative AI has introduced a transformative new approach enabling us to create novel biological functions. However, this newfound power is not without its challenges, including unpredictable 'hallucinations' in the generative process. How can we better harness generative biology’s potential, dramatically reduce errors, and leverage AI to rapidly construct intricate synbio functions and processes? Meet the groundbreaking SkyEngine and learn how new tools are paving the way for the next generation of biomachines.