Greg joined New England Biolabs in 2010 as a Postdoctoral Fellow under Tom Evans, who is now the Executive Director of Research. In that role, he initiated research into the kinetics of T4 DNA ligase, a project that has continued to the present day in his own research group. His Ph.D. advisor at MIT, JoAnne Stubbe, instilled in him a love of biochemistry and an appreciation of the small details of enzyme mechanism.Since becoming a Group Leader in in the NEB Research department, Greg Lohman has developed a program to investigate the mechanistic details of DNA ligases, with a focus on the in vitro function of the enzymes in high importance  molecular and synthetic biology applications. His research that has resulted in multiple new products and technical innovations, as well as numerous peer-reviewed publications on the mechanism and fidelity of DNA ligation. Recent focus of the lab has shifted to the optimization of high complexity DNA assembly for Synthetic Biology applicaitons, leveraging expertise in DNA ligation into devleopment of methods for Golden Gate Assembly of unprecidented complexity and flexibility. In cooperation with collaborators, we are exploring the rapid engineering of bacteriophages for accelerating biological study and supporting medical applications of phage therapeutics.