Computational Biology Scientist

Lastix Bio
Full Time
Paris

What we're looking for

We are seeking an exceptional computational biologist to join our R&D team and establish an in-silico modelling platform to accelerate the development of a high performing strain producing isoprenoids at industrial scale.

We post education and experience requirements along with a salary range for transparency and to allow candidates to have a sense of our expectations.If it doesn’t match perfectly, don’t hesitate to apply, we are flexible!

Responsibilities

  • Model new metabolisms at the genome scale and new-to-nature synthetic pathways in microbial strainsAs an extension, model the fermentor environment for industrial production
  • Integrate important quantitative metabolomics data in order to model, predict impact and suggest targets for optimising metabolic fluxes in order to increase production of isoprenoids
  • Work in a "design-build-test-learn” cycle with the wet lab teams to test pathways and develop solutions to overcome challenges

Qualifications

Hard skills

  • Proficiency in at least one data-related programming language (Python, R, SQL)
  • Ability to build data pipelines to integrate multiple data sources
  • Experience in modelling metabolic and biological processes:
    • Flux balance analysis, metabolic flux analysis
    • Genome sequence analysis including comparative genomics, genome assembly, alignment, gene structure and gene function annotation methods and tools
    • Enzyme kinetics, chemical data
  • Ability to interface with the wet lab team
  • Bonus: experience in CO2 fixation/reduction and C1/C2 metabolism
  • Bonus: experience modelling industrial fermentation
  • Bonus: professional experience in startup or industry

Soft skills

  • Great team player
  • Autonomy, action-oriented mindset, ability to take initiatives
  • Optimism and adaptability
  • Clear communication in English
  • Excellent organisational skills
  • Creativity and scientific curiosity

Benefits

  • Employee Stock Options (BSPCE)
  • Health insurance (Alan) 100% covered
  • Lunch voucher of 12€/day ( 7€/day paid by the company), 2 team lunches per months
  • 500€ per year for all your mobility needs (bike, subway, car-sharing…)
  • Individual training budget for skills development

Remote Position
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