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RA/Senior RA, Product Development, GRObio, Allston, Massachusetts

GRO Biosciences is leveraging breakthrough technologies from computational protein design and synthetic biology to develop best-in-class protein therapeutics with enhanced properties. The company has established multiple genomically recoded strains of bacteria that can incorporate non-standard amino acids into proteins to confer increased potency, stability, and targeted delivery. GRO Biosciences is applying its technology platform to develop improved protein therapeutics for diabetes, growth disorders and autoimmunity. The company, founded by Dr. George Church, is located at the Harvard Life Lab, a shared laboratory space for high-potential life sciences and biotechnology startups founded by Harvard faculty, alumni, students, and postdoctoral scholars.

RA/Senior RA, Product Development

GRO Biosciences (GRObio) is hiring a Research Associate (RA) or Senior RA to advance the company’s recoded organism technology. Recoded organisms enable efficient production of proteins using an expanded amino acid alphabet. Imagine working for a biotechnology company that doesn’t have to play by the rules of its competitors. With the tools at GRObio you’ll have the opportunity to solve problems once considered impossible. The individual selected for this position will work in Product Development and will facilitate early-stage product discovery and evaluation. Regular activities will include planning experiments and performing biomass generation, protein purification, protein characterization, and bioassays. This position will interface heavily with other team members of the working group. There is substantial growth opportunity within the company for the capable candidate. Long-term prospects for this position include:

  • Expanding core job responsibilities to additional aspects of R&D workflow
  • Planning, managing, and implementing high throughput, multiplexed workflows to enhance GRObio’s product evaluation pipeline Responsibilities
  • Work with the Product Development team to develop a discovery and evaluation pipeline
  • Express and purify products using a variety of biochemical techniques, including affinity chromatography, FPLC, and HPLC
  • Characterize product batches using biochemical assays including gel electrophoresis, capillary electrophoresis, thermal melt, mass spectrometry, and functional assays
  • Diligently record progress in our electronic lab notebook and LIMS systems
  • Clearly communicate results and recommendations with the team both in-person and online

Qualifications:

  • Requisite experience
  • MS degree (or BS/BA degree plus at least 1 year of research experience) in biology, microbiology, biotechnology, synthetic biology, systems biology, biological engineering, or other related field
  • Proficiency in molecular biology and microbiology
  • Protein purification o Biochemical and biophysical techniques for protein characterization
  • Desired experience
  • Exposure to industrial biotechnology
  • Assay/method development for protein characterization

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Lio Tariman

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